Original research
by
Grossarth, Sarah et al
Release Date
2023
Geography
USA
Language of Resource
English
Full Text Available
No
Open Access / OK to Reproduce
No
Peer Reviewed
Yes
Objective
To characterize the risk of postneonatal infant mortality among infants with a neonatal opioid withdrawal syndrome (NOWS) diagnosis or born to individuals with opioid use disorder (OUD).
Findings/Key points
The study team observed 1317 postneonatal infant deaths and incidence rates of 3.47 (OUD negative/NOWS negative, 375 718), 8.41 (OUD positive/NOWS positive, 4922); 8.95 (OUD positive/NOWS negative, 7196), and 9.25 (OUD negative/NOWS positive, 2239) per 1000 person-years. After adjustment, the risk of postneonatal death was elevated for all groups, relative to the unexposed: OUD positive/NOWS positive, OUD positive/NOWS negative, and OUD negative/NOWS positive.
Design/methods
Retrospective cohort study (n=390 075)
Keywords
Mortality
Parents/caregivers
Outcomes
