Welcome to our searchable resource and literature collection on safer supply and related topics.

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Previous research suggests that interpersonal relationships moderate treatment outcomes for opioid use disorder based on the nature and quality of the relationship.

Original research | 2024
Social benefits, Chronic pain

To develop a better understanding of the context of drug use, we interviewed safer supply program participants in Ottawa, Canada.

Original research | 2024
Safer supply, Harm reduction, Evidence base, About PWUD
Policy | 2024
Policy/Regulatory, Advocacy

This study utilized qualitative interviews to explore opioid withdrawal experiences and consequences among people who use opioids (PWUO) in Los Angeles County, USA.

Original research | 2024
Withdrawal, About PWUD

This study investigates the effectiveness of a short video targeting pharmacists that addresses implementation barriers for take-home naloxone (THN).

Original research | 2024
Harm reduction, About pharmacists

Point-of-care drug checking identifies components of a drug sample and delivers results consumers.

Original research | 2024
Drug checking, About PWUD, Barriers and enablers

To better identify individuals at risk and inform patients and clinicians about xylazine risk factors.

Original research | 2024
Illegal drugs, About PWUD

This study explores treatment experiences of people who use illicit stimulants (PWUS) to identify gaps and perceptions of prospective pharmaceutical stimulant substitution treatments (SST).

Original research | 2024
Stimulants, About PWUD, Substitution/OAT, Barriers and enablers

This study is the first one which compares patients' self-assessment of the risk of future opioid overdose with the hetero-assessment provided by healthcare professionals in a population of individ

Original research | 2024
Harm reduction, Overdose, About PWUD, Substitution/OAT
Report | 2024
Safer supply, Evidence base, About PWUD, About prescribers, Diversion

We examined prevalence and sociodemographic correlates of past year presumed xylazine effects and association with overdose and wound-related outcomes.

Original research | 2024
About PWUD, Overdose

We describe methadone and BUP/NX titration patterns and their associations with treatment outcomes among individuals with a prescription-type opioid use disorder (OUD).

Original research | 2024
Substitution/OAT, Outcomes

Little is known about demand-side issues, such as reasons for use and pathways to opioid use.

Original research | 2024
Youth, About PWUD

We performed a national survey of people who use drugs to evaluate common drug use preparation, harm reduction practices, and experiences with injection site infections.

Original research | 2024
Injecting drugs, About PWUD, Harm reduction

Community agencies and the City of Toronto opened COVID-19 isolation and recovery sites (CIRS) in March 2020.

Original research | 2024
Safer supply, About PWUD, About prescribers

Examine differences in neighborhood characteristics and services between overdose hotspot and non-hotspot neighborhoods and identify neighborhood-level population factors associated with increased

Original research | 2024
Overdose, Poverty, Housing, Social services
Commentary | 2024
Clinical guidance, About prescribers

One form of safe supply enlists clinicians to prescribe opioids so that people have access to drugs of known composition and strength.

Commentary | 2022
Safer supply, About prescribers, Harm reduction, Clinical guidance

Transgender and gender diverse (TGD) people who use drugs report barriers to accessing substance use treatment, including provider mistreatment.

Original research | 2024
About prescribers, 2SLGBTQI+

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